Si se liofiliza el producto ultimate contendrá, por lo menos, 950 miligramos de proteínas por gramo de producto. El método de preparación será tal que el producto last satisfaga los requisitos que se describen más adelante. Sea líquido o seco el producto final, la preparación, previa adición de un estabilizador idóneo, se calentará, en estado líquido y en su recipiente ultimate, hasta los 60° C ± zero,5° C, durante diez horas, con el fin de inactivar al agente causal de la hepatitis por inoculación. Durante la preparación no se agregará ninguna sustancia antiséptica o bacteriostática. (ii) se añadirá a 1 ml una discreta cantidad de trombina o de cloruro cálcico; la coagulación que se produzca entonces se podrá acelerar por incubación a 37º C.
Cuando se utiliza como disolvente de medicamentos y/o diluyente de soluciones para administración parenteral, antes de administrarse, se debe controlar la osmolaridad de la solución final y ajustar siempre que sea posible, su isotonicidad con la del plasma. La naturaleza del medicamento que se añada al agua para preparaciones inyectables determinará la probabilidad de que aparezca cualquier otra reacción adversa. Antes de la disolución de un medicamento, es necesario comprobar que este sea soluble y compatible con el agua para preparaciones inyectables. Su médico disolverá o diluirá otro medicamento en el agua para preparaciones inyectables antes de que se le administre el medicamento ya preparado. Los efectos sobre la capacidad para conducir y utilizar máquinas están relacionados con los medicamentos disueltos/diluidos. El otro día, me vi en la tesitura de hacer de guía de un nutrido grupo de visitantes a nuestro Jardín Botánico.
De ahí que esos productos hayan de prepararse a partir de mezclas de un número limitado de extracciones. El procedimiento de preparación debe ser tal que el producto satisfaga los requisitos previstos más adelante y, además, el producto ultimate no transmita la hepatitis por inoculación. Por otra parte, el método de preparación será tal que los anticuerpos contenidos en el producto inicial aparezcan concentrados en cantidad idónea en el producto last. El procedimiento utilizado se considerará satisfactorio a este respecto, por lo que a cada preparación se refiere, titulando los anticuerpos correspondientes cuando menos a un virus y a una toxina bacteriana en los productos inicial y last. Se elegirán anticuerpos para los cuales existan métodos de titulación acreditados.
La otra peculiaridad estructural consiste en la presencia de un átomo de flúor sobre el anillo aromático ligado al anillo de oxazolidinona (dicho anillo aromático es imprescindible para la actividad antibacteriana), que incrementa notablemente las propiedades antibacterianas. Es difícil no establecer un cierto paralelismo por este motivo con las antiguas quinolonas (ácido oxolínico, and so forth.), que vieron notablemente incrementado su espectro y potencia antibacteriana en las fluoroquinolonas (ciprfloxacino, etc.) con la easy introducción de este elemento. La fascitis necrosante es una infección particularmente destructiva que causa rápidamente la necrosis de tejidos profundos. La etiología es polimicrobiana e incluye cocos grampositivos y gramnegativos, y anaerobios, como Escherichia coli, Klebsiella pneumoniae y Pseudomonas aeruginosa. Alrededor del 10% está producida por Streptococcus pyogenes, y puede evolucionar a gangrena estreptocócica. Las lesiones menores, como los forúnculos, se encuentran en alrededor del 20% de los pacientes antes de que presenten una fascitis necrosante.
Debido a su alta afinidad por el tejido óseo y dental no se recomienda su administración a embarazadas y niños menores de 8 años, ya que se depositan en dientes y huesos en desarrollo. Pueden producir decoloración de los dientes (un problema estético que no alteraría la integridad del diente) u otras alteraciones, como displasia de encías, hipoplasia dental o deformidades óseas. Las tetraciclinas son generalmente bien toleradas y actualmente tienen relativamente pocos efectos secundarios. Antiguamente, las tetraciclinas tras dosis elevadas fueron causa frecuente de insuficiencia renal y toxicidad hepática, especialmente en mujeres embarazadas.
Tampoco si existe hipersensibilidad grave (por ejemplo, una reacción anafiláctica o cutánea grave) a cualquier otro antibiótico betalactámico (penicilinas o cefalosporinas). El pico se extrae tras 30 minutos de finalizar la infusión de la dosis correspondiente; el valle, previo a la administración de una dosis. Los valores son 5-12 µg/ml en pico y zero,5-1 µg/ml en valle. Cuando se administra en dosis única el pico es 2-3 veces mayor. Compatible con suero glucosado al 5 y el 10%, suero salino al zero,9% y solución de farmacia (glu-aa).
Posted: June 26, 2025 10:36 am
The issue of taksu is also one of honesty, for the artist and the viewer. An artist will follow his heart or instinct, and will not care what other people think. A painting that has a magic does not need to be elaborated upon, the painting alone speaks.
A work of art that is difficult to describe in words has to be seen with the eyes and a heart that is open and not influenced by the name of the painter. In this honesty, there is a purity in the connection between the viewer and the viewed.
As a through discussion of Balinese and Indonesian arts is beyond the scope of this catalogue, the reader is referred to the books listed in the bibliography. The following descriptions of painters styles are intended as a brief introduction to the paintings in the catalogue, which were selected using several criteria. Each is what Agung Rai considers to be an exceptional work by a particular artist, is a singular example of a given period, school or style, and contributes to a broader understanding of the development of Balinese and Indonesian paintng. The Pita Maha artist society was established in 1936 by Cokorda Gde Agung Sukawati, a royal patron of the arts in Ubud, and two European artists, the Dutch painter Rudolf Bonnet, and Walter Spies, a German. The society’s stated purpose was to support artists and craftsmen work in various media and style, who were encouraged to experiment with Western materials and theories of anatomy, and perspective.
The society sought to ensure high quality works from its members, and exhibitions of the finest works were held in Indonesia and abroad. The society ceased to be active after the onset of World War II. Paintings by several Pita Maha members are included in the catalogue, among them; Ida Bagus Made noted especially for his paintings of Balinese religious and mystical themes; and Anak Agung Gde Raka Turas, whose underwater seascapes have been an inspiration for many younger painters.
Painters from the village of Batuan, south of Ubud, have been known since the 1930s for their dense, immensely detailed paintings of Balinese ceremonies, daily life, and increasingly, “modern” Bali. In the past the artists used tempera paints; since the introduction of Western artists materials, watercolors and acrylics have become popular. The paintings are produced by applying many thin layers of paint to a shaded ink drawing. The palette tends to be dark, and the composition crowded, with innumerable details and a somewhat flattened perspective. Batuan painters represented in the catalogue are Ida Bagus Widja, whose paintings of Balinese scenes encompass the sacred as well as the mundane; and I Wayan Bendi whose paintings of the collision of Balinese and Western cultures abound in entertaining, sharply observed vignettes.
In the early 1960s,Arie Smit, a Dutch-born painter, began inviting he children of Penestanan, Ubud, to come and experiment with bright oil paints in his Ubud studio. The eventually developed the Young Artists style, distinguished by the used of brilliant colors, a graphic quality in which shadow and perspective play little part, and focus on scenes and activities from every day life in Bali. I Ketut Tagen is the only Young Artist in the catalogue; he explores new ways of rendering scenes of Balinese life while remaining grounded in the Young Artists strong sense of color and design.
The painters called “academic artists” from Bali and other parts of Indonesia are, in fact, a diverse group almost all of whom share the experience of having received training at Indonesian or foreign institutes of fine arts. A number of artists who come of age before Indonesian independence was declared in 1945 never had formal instruction at art academies, but studied painting on their own. Many of them eventually become instructors at Indonesian institutions. A number of younger academic artists in the catalogue studied with the older painters whose work appears here as well. In Bali the role of the art academy is relatively minor, while in Java academic paintings is more highly developed than any indigenous or traditional styles. The academic painters have mastered Western techniques, and have studied the different modern art movements in the West; their works is often influenced by surrealism, pointillism, cubism, or abstract expressionism. Painters in Indonesia are trying to establish a clear nation of what “modern Indonesian art” is, and turn to Indonesian cultural themes for subject matter. The range of styles is extensive Among the artists are Affandi, a West Javanese whose expressionistic renderings of Balinese scenes are internationally known; Dullah, a Central Javanese recognized for his realist paintings; Nyoman Gunarsa, a Balinese who creates distinctively Balinese expressionist paintings with traditional shadow puppet motifs; Made Wianta, whose abstract pointillism sets him apart from other Indonesian painters.
Since the late 1920s, Bali has attracted Western artists as short and long term residents. Most were formally trained at European academies, and their paintings reflect many Western artistic traditions. Some of these artists have played instrumental roles in the development of Balinese painting over the years, through their support and encouragement of local artist. The contributions of Rudolf Bonnet and Arie Smit have already been mentioned. Among other European artists whose particular visions of Bali continue to be admired are Willem Gerrad Hofker, whose paintings of Balinese in traditional dress are skillfully rendered studies of drapery, light and shadow; Carel Lodewijk Dake, Jr., whose moody paintings of temples capture the atmosphere of Balinese sacred spaces; and Adrien Jean Le Mayeur, known for his languid portraits of Balinese women.
Agung Rai feels that
Art is very private matter. It depends on what is displayed, and the spiritual connection between the work and the person looking at it. People have their own opinions, they may or may not agree with my perceptions.
He would like to encourage visitors to learn about Balinese and Indonesian art, ant to allow themselves to establish the “purity in the connection” that he describes. He hopes that his collection will de considered a resource to be actively studied, rather than simply passively appreciated, and that it will be enjoyed by artists, scholars, visitors, students, and schoolchildren from Indonesia as well as from abroad.
Abby C. Ruddick, Phd
“SELECTED PAINTINGS FROM THE COLLECTION OF THE AGUNG RAI FINE ART GALLERY”